MIPS Application Examples

MIPS systems are in use in a number of laboratories to support a variety of research applications. Listed below are several of these laboratories with links to their site to learn more about their research.

James Bruce’s lab at the University of Washington

Dr. Bruce’s pioneering developments in parallel excitation and detection of ion by FTICR is an example of MIPS system integration with a commercial mass spectrometer and generation of complex pulse sequence. In this example MIPS is trigger by the mass spectrometer and generates the required timing, this research also used MIPS ability to execute multiple pulse sequences and the experiment evolves.

Alexandre Shvartsburg’s lab at Wichita State University

Dr. Shvartsburg’s research in FAIMS has resulted in continuous advancements of the field. GAACE has developed MIPS based FAIMS power supplies to support his exciting research. The MIPS supply was used for the research that was featured on the cover of JASMS May 2016 issue

Matt Bush’s lab at the University of Washington

Dr. Bush’s research group has developed and applied SLIM technology toward their research in large proteins research elucidating collisional cross sectional values. This research was supported using MIPS systems to generate required RF/DC voltages as well as pulse sequence generation.

Brian Clowers’s lab

GAACE worked with Dr. Clowers to develop an open source BN gate pulse generator to support his research as well as provide capability to the research community. This is an excellent example of research collaboration.

Spectroglyph, LLC

Spectroglyph has design and developed exciting new MALDI imaging capability. GAACE provided a customized MIPS system to provide the needed RF/DC voltages as well as pulse sequence generation that this system required.

Pacific Northwest National Laboratory (PNNL)

The SLIM research developed at PNNL is an excellent example of MIPS systems in action. The SLIM research falls into two main areas, conventional ion mobility separation and traveling wave mobility separation. My goggle scholar page lists a number of papers and patents that describe this research, also follow the citations to see work from other labs in this area. All the traveling wave SLIM research has been done using MIPS systems. I have been closely involved in this development as can be seen from my name on many of the patents and papers. There are licensing options available for SLIM at PNNL, please see this link to learn more of opportunities. I have a number of ideas that could expand the capability and provide additional IP. If you are interested in pursuing research in this area I would love to discuss ways we might partner. Our MIPS products will provide all the control electronics needed to get you started and provide a platform for your growth.

SLIM technology will allow detection of ions with a simple current amplifier. This has great potential but also challenges due to all the RF voltages and Twave switching voltages present in the system. GAACE has done a great deal of work in the area of low noise detection and has ideas that could provide unique high performance detection capability. This would allow the development of portable SLIM based systems for a wide range of applications.

MIPS systems are very versatile and can be configured for many mass spec research activities. We are always happy to discuss your application and how our capabilities can help. Our specialty is research and we aim our products toward research institutions. We know you will find our rates the most competitive in the industry.

GAACE is very interested in supporting and promoting mass spec research. This community has provided us a very rewarding career and allowed us to provide research support to the community at very low rates. If you need help with a project please call, even if all you want to do is discuss your problem and get ideas to move your project forward. We are also interested in doing pro bono work if you have the right problem and cause we may be interested in contributing. Our strength is in circuit design and real-time control of systems so give us a call I bet we can help you move your project forward!